Wow That is HUGE ! You will probably have to do this in sections and then assemble them using a poster print software. I say this because even on a Monster of a computer all that detail over multiple layers really adds up to HUGE file sizes and really long render times and quite possibly program and / or system crashes ! Yes that is a run on sentence !! I would suggest leaving all the details and Textures ETC until last and concentrate on the general layout first. Cut it into slice as if for a web page. Then detail one section at a Time.