Well, I'm certainly late to this thread, but I've played 4E consistently for almost a year now (had a false start with a set of random socially awkward folks that imploded when 4E launched), and am having a blast. I played AD&D 2nd Edition back in high school and then a semester's worth of 3E in college, but it's nice to be back.
I spent the majority of my time as a half-orc sorcerer, but after a campaign restart two months ago, I'm now playing a human shaman MCed invoker and having a ball.